importin beta
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Official Full Name
importin beta [Drosophila melanogaster] -
Overview
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a a classical nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits. Each of these subunits are part of the karyopherin family of proteins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. -
Synonyms
importin beta;Importin β
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KPNB1-1050H | Recombinant D. melanogaster importin beta, His-tagged | E.coli | Drosophila | His |
|
Involved Pathway
importin beta involved in several pathways and played different roles in them. We selected most pathways importin beta participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with importin beta were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
importin beta has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by importin beta itself. We selected most functions importin beta had, and list some proteins which have the same functions with importin beta. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
importin beta has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with importin beta here. Most of them are supplied by our site. Hope this information will be useful for your research of importin beta.
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